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April 25, 2017

Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types

  • Other
  • Nanotechnology

Phys.org – Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.

The nanovaccine consists of tumor antigens - tumor proteins that can be recognized by the immune system - inside a synthetic polymer nanoparticle. Nanoparticle vaccines deliver minuscule particulates that stimulate the immune system to mount an immune response. The goal is to help people's own bodies fight cancer.

"What is unique about our design is the simplicity of the single-polymer composition that can precisely deliver tumor antigens to immune cells while stimulating innate immunity. These actions result in safe and robust production of tumor-specific T cells that kill cancer cells," said Dr. Jinming Gao, a Professor of Pharmacology and Otolaryngology in UT Southwestern's Harold C. Simmons Comprehensive Cancer Center.

Read more at Phys.org.