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The National Academy of Sciences (NAS) and the National Academy of Medicine (NAM) established the Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations, which delivered a report entitled "Human Genome Editing: Science, Ethics, and Governance". The report considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

(Content modified from the National Academies Press)