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September 8, 2017 8:30 am

Workshop: National Academies Board on Health Sciences Policy, Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier

  • Other
  • Nanotechnology
  • Neuroscience

The Board on Health Sciences Policy within the National Academies of Sciences, Engineering, and Medicine will host a public workshop titled "Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier". This workshop will bring together key experts from academia, government, the biotechnology and pharmaceutical sector, disease-focused organizations, and other interested stakeholders to explore current development of novel methods for traversing the blood-brain barrier to deliver therapeutics for nervous system disorders and identify potential opportunities for moving the field forward.

Workshop objectives include:

  • Provide an overview of current knowledge on the role of the brain-blood barrier biology and delivery mechanisms examining gaps in our current knowledge that future research may address.
  • Discuss brain-blood barrier passive and active mechanisms that challenge development and delivery of effective therapeutic interventions to central nervous system targets.
  • Highlight current data and innovative approaches for delivery of therapeutics across the brain-blood barrier harnessing methods including chemical modifications, Trojan horse approaches, physical targeting and disruption, nanoparticles, ultrasound, and other technologies.
  • Explore potential opportunities for catalyzing development of novel treatments that cross the blood-brain barrier--from the preclinical to clinical phase--with an emphasis on risks, levers, and potential collaborative efforts among sectors.

More information is available via the National Academies's website.